In Holguín Province, 19 viral genotypes were detected, of which 11 (57.9%) were high-risk HPV. Frequencies of the different genotypes in this province are shown in Figure 2C. Genotype 16 was less frequent in women in Holguín than those in Havana and Villa Clara. In Villa Clara Province, 20 HPV genotypes were identified, of which 12 (60%) were high-risk HPV. Figure 2B shows frequency of diagnosis for the different genotypes in this province. Prevalence of HPV 31 and 33 were greater in women in Villa Clara compared with the other provinces studied.
In order to reach women at the grassroots, the FMC initiated a series of study groups at the neighborhood level. After 1959, domestic service was viewed as degrading and exploitative. Maids began to be described as slaves who were exploited by long hours of work, abusive treatment and low pay.
It is also true that Havana does not have the greatest percentage of single women, nor those who began sexual relations at age ≤15 years, although it is where the greatest frequencies of infection are seen within these categories by province. Although vaccination is the most efficient prophylactic method, because it protects against infection from seven oncogenic HPV genotypes, it is not the only means. HPV infection frequency was greater in students, single or reported having had more than three sexual partners. Student status does not seem to be an independent risk factor in itself, because student status probably coincides with young age, singleness and probably higher-risk sexual behavior. Sexual relations with a large number of partners is a risk factor for HPV and other STIs.
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Low-risk HPV genotypes were found in 27% (20/74) of positive cases, with coinfection with high-risk HPV in 6.7% (5/74) Coinfections with several HPV genotypes were identified in 3.4% (17/500) of all women in the sample and in 23% (17/74) of infected women . Ethics The project was approved by IPK’s Research Ethics Committee. Study participants provided written informed consent per the Declaration of Helsinki and guidelines of the Council for International Organizations of Medical Sciences. The signed document contained the necessary information about the research study, including possible benefits and risks. Participants were informed that they could withdraw from the study at any time without penalty or any effect on their care and treatment. Data were saved following the principle of confidentiality and individual identities were not revealed. Sampling was done by a trained clinician, taking the necessary care to minimize risks in accordance with good clinical practice standards.
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